Gene information
Official symbol GABRG3
Official full name gamma-aminobutyric acid type A receptor subunit gamma3
Gene type protein-coding gene
Chromosome15q12
Gene familyGamma-aminobutyric acid type A receptor subunits
Resources
Entrez Gene 2567
HGNC HGNC:4088
Ensembl ENSG00000182256
Vega OTTHUMG00000044462
UCSC uc001zbg.3
GO terms: 35 records
GO Description Category LogP Number of genes Detail
GO:0005216 ion channel activity GO Molecular Functions -2.12987867 14 More
GO:0005253 anion channel activity GO Molecular Functions -1.99792626 5 More
GO:0005254 chloride channel activity GO Molecular Functions -1.59770764 4 More
GO:0006821 chloride transport GO Biological Processes -1.70687084 5 More
GO:0007268 chemical synaptic transmission GO Biological Processes -4.44678751 35 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0015103 inorganic anion transmembrane transporter activity GO Molecular Functions -2.09965422 7 More
GO:0015108 chloride transmembrane transporter activity GO Molecular Functions -1.77380598 5 More
GO:0015267 channel activity GO Molecular Functions -2.12225487 15 More
GO:0015276 ligand-gated ion channel activity GO Molecular Functions -3.44721899 9 More
GO:0015318 inorganic molecular entity transmembrane transporter activity GO Molecular Functions -2.11605072 20 More
GO:0015698 inorganic anion transport GO Biological Processes -1.84892626 7 More
GO:0022803 passive transmembrane transporter activity GO Molecular Functions -2.11455525 15 More
GO:0022834 ligand-gated channel activity GO Molecular Functions -3.44721899 9 More
GO:0022836 gated channel activity GO Molecular Functions -2.68852033 13 More
GO:0030425 dendrite GO Cellular Components -4.55233052 48 More
GO:0031252 cell leading edge GO Cellular Components -1.97716247 28 More
GO:0032589 neuron projection membrane GO Cellular Components -1.92506134 4 More
GO:0032590 dendrite membrane GO Cellular Components -2.48632122 4 More
GO:0034707 chloride channel complex GO Cellular Components -2.11523204 4 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0045211 postsynaptic membrane GO Cellular Components -5.83105498 30 More
GO:0060078 regulation of postsynaptic membrane potential GO Biological Processes -2.74505261 11 More
GO:0097060 synaptic membrane GO Cellular Components -5.94418548 20 More
GO:0097447 dendritic tree GO Cellular Components -4.82959150 49 More
GO:0098656 anion transmembrane transport GO Biological Processes -1.61106579 8 More
GO:0098661 inorganic anion transmembrane transport GO Biological Processes -1.97776028 5 More
GO:0098916 anterograde trans-synaptic signaling GO Biological Processes -4.44678751 35 More
GO:0098982 GABA-ergic synapse GO Cellular Components -3.15908473 6 More
GO:0099240 intrinsic component of synaptic membrane GO Cellular Components -5.23284212 12 More
GO:0099536 synaptic signaling GO Biological Processes -6.00976162 42 More
GO:0099537 trans-synaptic signaling GO Biological Processes -5.17038357 38 More
GO:0099699 integral component of synaptic membrane GO Cellular Components -4.78109966 11 More
GO:1902476 chloride transmembrane transport GO Biological Processes -2.50383130 5 More
GO:1990351 transporter complex GO Cellular Components -2.10211936 13 More
KEGG pathways: 3 records
KEGG Description Category LogP Number of genes Detail
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04727 GABAergic synapse KEGG Pathway -1.95788592 5 More
hsa05032 Morphine addiction KEGG Pathway -3.96184640 13 More
Drug-Gene interaction
view
Related drugs: 72 records
Drug name Interaction type Source PMID View
acamprosate calcium ChemblInteractions view
adinazolam potentiator TdgClinicalTrialTEND 61484006320036 view
adipiplon partial agonist TdgClinicalTrialChemblInteractions view
alprazolam positive modulator TdgClinicalTrialChemblInteractionsTEND view
azd-3043 TTD view
azietomidate DTC 16884293 view
bentazepam TTD view
brexanolone TTD view
bromazepam potentiator TdgClinicalTrialTEND 18384456 view
butabarbital sodium positive modulator ChemblInteractions view
butalbital positive modulator ChemblInteractions view
chlordiazepoxide positive modulator TdgClinicalTrialChemblInteractionsTEND view
chlordiazepoxide hydrochloride positive modulator ChemblInteractions view
cinolazepam potentiator TdgClinicalTrialTEND 7849137 view
clobazam positive modulator TdgClinicalTrialChemblInteractionsTEND view
clomethiazole TTD view
clonazepam positive modulator TdgClinicalTrialChemblInteractionsTEND view
clorazepate dipotassium positive modulator ChemblInteractions view
clorazepic acid TdgClinicalTrialTEND view
clotiazepam potentiator TdgClinicalTrialTEND 18855614 view
desflurane positive modulator ChemblInteractions view
diazepam positive modulatorpotentiator TdgClinicalTrialChemblInteractionsTEND 1838445611752090 view
enflurane ChemblInteractions view
estazolam positive modulatorpotentiator TdgClinicalTrialChemblInteractionsTEND 6398542889803 view
eszopiclone positive modulator ChemblInteractions view
etazolate TTD view
ethchlorvynol ChemblInteractions view
etomidate DTCChemblInteractionsTTD 16884293 view
fludiazepam potentiator TdgClinicalTrialTEND 2857046 view
flumazenil ChemblInteractionsTTD view
flurazepam potentiator TdgClinicalTrialTEND 1838445611752090 view
ganaxolone TTD view
glutethimide ChemblInteractions view
halazepam potentiatorpositive modulator TdgClinicalTrialChemblInteractionsTEND 67383022867566 view
halothane positive modulator ChemblInteractions view
isoflurane positive modulator ChemblInteractions view
lorazepam positive modulator TdgClinicalTrialChemblInteractionsTEND view
lorediplon positive modulator ChemblInteractions view
mebutamate TTD view
meprobamate agonist ChemblInteractions view
metharbital positive modulator ChemblInteractionsTTD view
methohexital sodium positive modulator ChemblInteractions view
methoxyflurane ChemblInteractions view
methyprylon positive modulator ChemblInteractions view
midazolam potentiator TdgClinicalTrialTEND 1838445611752090 view
midazolam hydrochloride positive modulator ChemblInteractions view
nitrazepam potentiator TdgClinicalTrialTEND 1838445611752090 view
ocinaplon TdgClinicalTrial view
oxazepam positive modulatorpotentiator TdgClinicalTrialChemblInteractionsTEND 1838445611752090 view
pagoclone TTD view
pentobarbital positive modulator ChemblInteractions view
pentobarbital sodium positive modulator ChemblInteractions view
pf-06372865 agonist ChemblInteractions view
prazepam positive modulatorpotentiator TdgClinicalTrialChemblInteractionsTEND 7773620 view
primidone positive modulator ChemblInteractions view
propofol positive modulator ChemblInteractions view
quazepam potentiatorpositive modulator TdgClinicalTrialChemblInteractionsTEND 30176902892106 view
remimazolam TdgClinicalTrialTTD view
resequinil inverse agonist ChemblInteractions view
saripidem TTD view
secobarbital sodium positive modulator ChemblInteractions view
sevoflurane positive modulator ChemblInteractions view
stiripentol TTD view
talbutal positive modulator ChemblInteractionsTTD view
temazepam positive modulatorpotentiator TdgClinicalTrialChemblInteractionsTEND 1838445620138190 view
thiamylal TTD view
thiamylal sodium positive modulator ChemblInteractions view
thiopental sodium positive modulator ChemblInteractions view
topiramate ChemblInteractions view
triazolam potentiatorpositive modulator TdgClinicalTrialChemblInteractionsTEND 1838445611752090 view
triclofos sodium ChemblInteractions view
zolpidem TTD view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg02281208 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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